Handgun grip options vary by the type of handgun you're shooting. Hand size also comes into play for each type of weapon.
You want the grip to place the gun to allow for correct trigger pull and finger placement. Making sure your own handgun -- whether pistol or revolver -- fits is paramount.
Interchangeable grips can greatly help you to fit the weapon properly to your hand and many aftermarket options are available as well as some directly from the gun's manufacturer. In this video, you'll get some expert tips on how to improve your handgun's fit using the grip options available.